Preprocessing and feature extraction

asari

Process high-resolution mass-spectrometry data into aligned feature tables.

LC-MSPython packageCommand lineSource available with restrictions

Overview

Asari uses mass alignment and a composite representation of chromatographic signals to extract features across samples. Its default workflow focuses on LC-MS feature processing.

What can this tool do?

Peak or feature detectionRetention-time alignment

Common uses

  • Build a feature table from centroided LC-MS files.
  • Prepare data for downstream quality control and statistics.

Scientific fit

Primary function

Preprocessing and feature extraction

Data compatibility

Inputs

Mass spectra

Outputs

Feature or peak table

Input formats

mzML

Output formats

CSV or TSV, JSON

Scope and considerations

Designed for

  • Build a feature table from centroided LC-MS files.

Not designed for

  • Assigning confirmed chemical structures from feature detection alone.

Important requirements

  • Centroided mzML data and a compatible Python environment.

Considerations

  • Check mass tolerances, chromatography and acquisition mode against the workflow; default processing and specialized workflows differ.

Access and documentation

Source and installation instructions are public; consult the repository license for the version used.

Evidence and review

Documentation-based editorial review on 7 September 2026. Scope and limitations summarize the linked official sources; software execution and developer verification were not assessed.

Core publications

Resource papers, direct updates and tool-specific methods. Selection policy.

  1. Li S, Siddiqa A, Thapa M, et al. Trackable and scalable LC-MS metabolomics data processing using asari. Nat Commun 14, 4113 (2023). doi:10.1038/s41467-023-39889-1

Related tools

Entry history

Changes to this catalogue entry, not the tool's software release history. Acceptance and editorial review are separate.

  1. 2026-09-08 · Entry update

    Audit core publications across existing tools

    View change · Entry at this revision
  2. 2026-09-07 · First committed entry

    Add 50 documented metabolomics resources

    View change · Entry at this revision

Full GitHub history