Pathway and biological interpretation

Lipid Mini-On

Group lipid names into ontology terms and test enrichment using a locally run Shiny interface.

Platform-independentLipidomicsWeb applicationOpen source

Overview

Lipid Mini-On uses the Rodin R package to group lipid names by classes and chain properties, perform enrichment tests and visualize lipid-to-term relationships. Current repository instructions describe local execution.

What can this tool do?

Pathway enrichmentNetwork visualization

Common uses

  • Compare a lipid query set against its measured background.
  • Explore lipid classes and chain properties associated with a selected set.

Scientific fit

Primary function

Pathway and biological interpretation

Analysis types

Lipidomics

Data compatibility

Inputs

Compound list or annotations

Outputs

Statistical results, Human-readable report

Input formats

CSV or TSV

Output formats

Ontology enrichment tables and interactive plots

Scope and considerations

Designed for

  • Ontology enrichment of lipid name lists.

Not designed for

  • Raw MS data processing or direct metabolic-flux inference.

Important requirements

  • Query and universe lipid lists in the documented CSV layout, plus local R dependencies.

Considerations

  • Background selection and name parsing affect enrichment; inspect assignments before interpreting terms.

Access and documentation

Local browser interface served by R/Shiny. The current README requires R 4.x, RStudio, Rodin and listed R dependencies; do not assume the historical hosted endpoint remains available.

License: BSD-2-Clause

Evidence and review

Official documentation and dedicated software publications reviewed on 2026-09-11. No installation, uploaded dataset or independent benchmark was run.

Core publications

Resource papers, direct updates and tool-specific methods. Selection policy.

  1. Clair G, Reehl S, Stratton KG, et al. Lipid Mini-On: mining and ontology tool for enrichment analysis of lipidomic data. Bioinformatics 35, 4507–4508 (2019). doi:10.1093/bioinformatics/btz250 PMID 30977807

Related tools

Entry history

Changes to this catalogue entry, not the tool's software release history. Acceptance and editorial review are separate.

  1. 2026-09-11 · First committed entry

    Complete supplied lipidomics group and prioritize Ask Navigator

    View change · Entry at this revision

Full GitHub history