Overview
LOTUS harmonizes natural-product occurrence knowledge and makes it available through a dedicated interface and Wikidata, supporting community curation.
What can this tool do?
Common uses
- Explore reported natural products for a taxon.
- Build candidate lists with traceable literature context.
Scientific fit
Primary function
Reference data and database search
Data compatibility
Inputs
Compound list or annotations, Molecular structures
Outputs
Compound list or annotations, Molecular structures
Input formats
Other, Structures, taxa or occurrence queries
Output formats
Other, Structure-organism-reference records
Scope and considerations
Designed for
- Explore reported natural products for a taxon.
Not designed for
- Treating database absence as evidence that an organism cannot produce a molecule.
Important requirements
- A chemical structure, taxon or other supported query.
Considerations
- Coverage reflects published and curated observations; taxonomic assignments and occurrence records need source review.
Access and documentation
Open knowledge initiative; preserve provenance and consult the terms of the selected export.
From tool to strategy
Strategies using LOTUS
Evidence and review
Documentation-based editorial review on 7 September 2026. Scope and limitations summarize the linked official sources; software execution and developer verification were not assessed.
Core publications
Resource papers, direct updates and tool-specific methods. Selection policy.
- Rutz A, Sorokina M, Galgonek J, et al. The LOTUS initiative for open knowledge management in natural products research. Elife 11, e70780 (2022). doi:10.7554/eLife.70780
Related tools
Entry history
Changes to this catalogue entry, not the tool's software release history. Acceptance and editorial review are separate.
- 2026-09-08 · Entry update
Audit core publications across existing tools
View change · Entry at this revision - 2026-09-07 · First committed entry
Add 50 documented metabolomics resources
View change · Entry at this revision