Pathway and biological interpretation

PaintOmics

Visualize metabolomics alongside other omics layers on biological pathways.

Platform-independentMulti-omicsWeb applicationOpen source

Overview

PaintOmics maps processed metabolite and other omics measurements onto KEGG, Reactome and MapMan pathways for integrated enrichment and visualization.

Also known as: PaintOmics 4

What can this tool do?

Pathway enrichmentNetwork visualization

Common uses

  • Visualize metabolomics alongside other omics layers on biological pathways.

Scientific fit

Primary function

Pathway and biological interpretation

Analysis types

Multi-omics

Data compatibility

Inputs

Feature or peak table, Compound list or annotations, Sample metadata

Outputs

Statistical results, Human-readable report

Input formats

Processed omics matrices with compatible metabolite/gene identifiers

Output formats

Pathway visualizations and enrichment results

Scope and considerations

Designed for

  • PaintOmics maps processed metabolite and other omics measurements onto KEGG, Reactome and MapMan pathways for integrated enrichment and visualization.

Not designed for

  • Raw MS processing or confirmation of metabolite identities.

Important requirements

  • Processed measurements with mapped identifiers and compatible experimental conditions across omics layers.
  • A supported organism/pathway database; ambiguous metabolite mappings require review.

Considerations

  • This entry describes the published pathway-analysis core. The current release adds an AI interpretation agent; that extension was not independently validated here.
  • Enrichment and pathway co-occurrence do not demonstrate causal regulation or metabolic flux.

Access and documentation

GPL-3.0 license verified in the official repository. External pathway databases and optional AI services have separate terms; no service execution test.

License: GPL-3.0

Evidence and review

Enveda intake checked against official documentation, license information and primary DOI/title/year on 2026-10-22. Editorial review only; no execution or independent benchmark.

Core publications

Resource papers, direct updates and tool-specific methods. Selection policy.

  1. PaintOmics 4: new tools for the integrative analysis of multi-omics datasets supported by multiple pathway databases. Nucleic Acids Research (2022). doi:10.1093/nar/gkac352

Related tools

Entry history

Changes to this catalogue entry, not the tool's software release history. Acceptance and editorial review are separate.

  1. 2026-10-23 · First committed entry

    Add ten reviewed Enveda tools with input and applicability limits

    View change · Entry at this revision

Full GitHub history